DNA Testing Technology | Whole Genome Sequencing | GenoConnect
GenoConnect uses Whole Genome Sequencing with multiple coverage tiers — from accessible 1× WGS to hospital-grade 30× — for accurate DNA testing in India.
GenoConnect uses Whole Genome Sequencing (WGS) — the most comprehensive DNA analysis technology available. The depth of your results depends on the sequencing tier you choose. WGS reads the complete sequence of your DNA — all ~3.2 billion base pairs across every chromosome — uncovering common and rare variants that targeted genotyping arrays would miss.
What is Whole Genome Sequencing?
The critical variable in WGS is sequencing depth (coverage) — how many times each position in the genome is independently read. Greater depth means more confidence in every variant call and more rare variants discovered. GenoConnect offers tiers from an accessible 1× standard up to the 30× gold standard used in hospitals.
Sequencing Tiers
- Standard 1× WGS: Full genome scan for ancestry, heritage, and common trait & wellness variants (~95% genome coverage).
- Enhanced Discovery 5× WGS: Higher confidence and deeper rare-variant discovery for richer trait and health insights.
- Clinical Grade 5× WGS + 100× WES: Combines whole-genome coverage with ultra-deep exome sequencing for clinical-grade coding-region analysis.
- Premium 15× WGS: Clinical-grade depth across the entire genome with high-confidence SNPs, indels, and structural variants.
- Hospital Grade 30× WGS: The standard used by hospitals and research institutions for maximum variant-call accuracy.
Coverage Depth and Result Accuracy
All tiers use the same physical kit and sample collection process. The difference is entirely in how your sample is processed in the lab — more coverage means deeper insight and higher confidence. Higher depth tiers provide clinical-grade accuracy and enable re-analysis as science advances, without collecting a new sample.
Why Whole Genome Sequencing?
- Reads the entire genome — not just pre-selected markers
- Detects rare and novel variants missed by older genotyping chips
- One sample, one test — no need for multiple targeted assays
- Future-proof: as science advances, more insights can be extracted from the same raw data
- Higher depth tiers provide clinical-grade accuracy
- Enables re-analysis without collecting a new sample